国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次,處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果,再次證明GenScript 有能力幫助業內科學家Make research easy.

Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth

J Nanobiotechnology. 2023-01; 
Hyukjun Choi, Mirae Yeo, Yujin Kang, Hyo Jeong Kim, Seong Guk Park, Eunjung Jang, Sung Ho Park, Eunhee Kim, Sebyung Kang
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis … The endotoxin was removed by using Triton X-114 (Sigma, USA), and the levels of the resulting samples were quantified by using a Limulus Amebocyte Lysate assay (GenScript, … Get A Quote

摘要

The aggressive proliferation of tumor cells often requires increased glucose uptake and excessive anaerobic glycolysis, leading to the massive production and secretion of lactate to form a unique tumor microenvironment (TME). Therefore, regulating appropriate lactate levels in the TME would be a promising approach to control tumor cell proliferation and immune suppression. To effectively consume lactate in the TME, lactate oxidase (LOX) and catalase (CAT) were displayed onto Aquifex aeolicus lumazine synthase protein nanoparticles (AaLS) to form either AaLS/LOX or AaLS/LOX/CAT. These complexes successfully consumed lactate produced by CT26 murine colon carcinoma cells under both normoxic and hypoxic conditions.... More

關鍵詞

Catalase, Lactate consumption, Lactate oxidase, Tumor microenvironment, Tumor suppression
              主站蜘蛛池模板: 寿宁县| 鄯善县| 巢湖市| 铜梁县| 北辰区| 日照市| 廉江市| 金平| 和田市| 普兰店市| 太仓市| 梓潼县| 德钦县| 西盟| 信丰县| 突泉县| 武胜县| 城市| 凯里市| 元朗区| 平潭县| 寻乌县| 长垣县| 林州市| 贵港市| 上饶市| 邢台县| 夏津县| 黑水县| 鹤庆县| 屯昌县| 冕宁县| 绵竹市| 满洲里市| 教育| 寿光市| 吉安市| 沙坪坝区| 如东县| 武鸣县| 吉水县|