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Examination of SARS-CoV-2 serological test results from multiple commercial and laboratory platforms with an in-house serum panel

Access Microbiol. 2024-02; 
Sandra N Lester, Megan Stumpf, Brandi D Freeman, Lisa Mills, Jarad Schiffer, Vera Semenova, Tao Jia, Rita Desai, Peter Browning, Bailey Alston, Muyiwa Ategbole, Shanna Bolcen, Alexander Chen, Ebenezer David, Panagiotis Manitis, Heather Tatum, Yunlong Qin, Briana Zellner, Jan Drobeniuc, Alexandra Tejada-Strop, Payel Chatterjee, Punya Shrivastava-Ranjan, M Harley Jenks, Laura K McMullan, Mike Flint, Christina F Spiropoulou, Glenn P Niemeyer, Bonnie J Werner, Christopher J Bean, Jeffrey A Johnson, Alex R Hoffmaster, Panayampalli S Satheshkumar, Amy J Schuh, S Michele Owen, Natalie J Thornburg
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Proteins, Expression, Isolation and Analysis … SARS-CoV-2 S protein, its domains, or the N protein [18]. The … the reference standard and GenScript USA Inc. recommended … the spike (S) protein as opposed to antibodies against the … Get A Quote

摘要

Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) is a novel human coronavirus that was identified in 2019. SARS-CoV-2 infection results in an acute, severe respiratory disease called coronavirus disease 2019 (COVID-19). The emergence and rapid spread of SARS-CoV-2 has led to a global public health crisis, which continues to affect populations across the globe. Real time reverse transcription polymerase chain reaction (rRT-PCR) is the reference standard test for COVID-19 diagnosis. Serological tests are valuable tools for serosurveillance programs and establishing correlates of protection from disease. This study evaluated the performance of one in-house enzyme linked immunosorbent assay (ELIS... More

關(guān)鍵詞

COVID-19, SARS-CoV-2, antibodies, immunoassays, neutralization assay, serological tests
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