国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務(wù)及產(chǎn)品已被Cell, Nature, Science, PNAS等1300多家生物醫(yī)藥類雜志引用近萬次,處于行業(yè)領(lǐng)先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學(xué)等約400家全球著名機(jī)構(gòu)使用GenScript的基因合成、多肽服務(wù)、抗體服務(wù)和蛋白服務(wù)等成功地發(fā)表科研成果,再次證明GenScript 有能力幫助業(yè)內(nèi)科學(xué)家Make research easy.

Direct visualization by FRET-FLIM of a putative mechanosome complex involving Src, Pyk2 and MBD2 in living MLO-Y4 cells

PLoS ONE. 2021-12; 
Richard N Day, Kathleen H Day, Fredrick M Pavalko
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis DNA in the sample was sheared by repeated passage through a 25g needle (to reduce viscosity of the sample) and approximately 20 ug of sample per lane was loaded onto 4–12% gradient polyacrylamide gels (GenScript, Piscataway, NJ, USA) Get A Quote

摘要

Earlier, we proposed the "mechanosome" concept as a testable model for understanding how mechanical stimuli detected by cell surface adhesion molecules are transmitted to modulate gene expression inside cells. Here, for the first time we document a putative mechanosome involving Src, Pyk2 and MBD2 in MLO-Y4 osteocytes with high spatial resolution using FRET-FLIM. Src-Pyk2 complexes were concentrated at the periphery of focal adhesions and the peri-nuclear region. Pyk2-MBD2 complexes were located primarily in the nucleus and peri-nuclear region. Lifetime measurements indicated that Src and MBD2 did not interact directly. Finally, mechanical stimulation by fluid flow induced apparent accumulation of Src-Pyk2 prot... More

關(guān)鍵詞

              主站蜘蛛池模板: 河南省| 区。| 芒康县| 彰化市| 麻江县| 绥芬河市| 新河县| 阜城县| 安龙县| 津市市| 郎溪县| 正阳县| 南昌县| 马关县| 镇坪县| 广东省| 阿鲁科尔沁旗| 平阴县| 南京市| 海林市| 星子县| 普兰县| 隆子县| 印江| 山阴县| 会泽县| 娄底市| 伊春市| 盐池县| 清涧县| 唐山市| 汝南县| 驻马店市| 西吉县| 临沧市| 栾城县| 通许县| 五指山市| 洛宁县| 出国| 万全县|