国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次,處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果,再次證明GenScript 有能力幫助業內科學家Make research easy.

Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1

Cell Rep. 2021-12; 
Kyung-Mi Choi, Jung Hak Kim, Xiangmudong Kong, Meltem Isik, Jin Zhang, Hee-Woong Lim, John C Yoon
Products/Services Used Details Operation
Catalog Antibody ?anti-Flag (GenScript; A00187) Get A Quote

摘要

Manipulation of energy-dissipating adipocytes has the potential to produce metabolic benefits. To this end, it is valuable to understand the mechanisms controlling the generation and function of thermogenic fat. Here, we identify Letm1 domain containing 1 (Letmd1) as a regulator of brown fat formation and function. The expression of Letmd1 is induced in brown fat by cold exposure and by β-adrenergic activation. Letmd1-deficient mice exhibit severe cold intolerance concomitant with abnormal brown fat morphology, reduced thermogenic gene expression, and low mitochondrial content. The null mice exhibit impaired β3-adrenoreceptor-dependent thermogenesis and are prone to diet-induced obesity and defective glucose ... More

關鍵詞

Letmd1, brown fat, thermogenesis
              主站蜘蛛池模板: 汶上县| 宕昌县| 清水县| 望奎县| 忻州市| 灵山县| 阿图什市| 金坛市| 绥江县| 桑日县| 晴隆县| 哈密市| 北票市| 原平市| 泾阳县| 恩施市| 龙井市| 上高县| 广饶县| 塔城市| 收藏| 临城县| 连山| 靖江市| 拉萨市| 乌恰县| 阿拉善盟| 正定县| 南皮县| 山东| 平遥县| 道孚县| 富宁县| 宁河县| 航空| 克什克腾旗| 莲花县| 汤阴县| 阿拉善盟| 石林| 盱眙县|