国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次,處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果,再次證明GenScript 有能力幫助業內科學家Make research easy.

GITRL impairs the immunosuppressive function of MDSCs via PTEN-mediated signaling pathway in experimental Sj?gren syndrome

Inflamm Res. 2022-10; 
Jie Tian, Beibei Zhang, Qingfang Yuan, Xueqing Sun, Na Peng, Bo Zhu, Chang Liu, Xiaoran Wang, Man Han, Meng Cao, Fan Xiao, Shengjun Wang, Ke Rui, Liwei Lu
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis … Endotoxin was removed by Toxin Eraser endotoxin removal resin (GenScript) and detected by E-TOXATE Kits (Sigma-Aldrich). The endotoxin levels of both GITRL and control are less … Get A Quote

摘要

background: Recent studies have revealed a role of the ligand for glucocorticoid-induced TNFR family-related protein (GITRL) in mediating functional dysregulations of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of primary Sj?gren syndrome (pSS), but the underlying molecular mechanism is largely unclear. In this study, we aimed to elucidate GITRL-mediated signaling pathways in MDSCs during the development of experimental SS (ESS). methods: MDSCs were stimulated with recombinant GITRL, the activation of PTEN, AKT and STAT3 in MDSCs was analyzed by Western blot. MDSCs with different treatment were adoptively transferred to ESS mice. ELISA was used to detect the level of autoantibodies. Proportion... More

關鍵詞

Autoimmune disease, GITRL, MDSCs, PTEN, Sj?gren’s syndrome
              主站蜘蛛池模板: 青川县| 合川市| 安多县| 日土县| 盈江县| 资源县| 凌源市| 微博| 巴楚县| 罗平县| 潢川县| 五莲县| 沙河市| 鄂尔多斯市| 西平县| 武宣县| 奉化市| 赫章县| 偏关县| 江西省| 灵川县| 绥德县| 南靖县| 大埔县| 富锦市| 密山市| 新营市| 甘德县| 丰原市| 巴林左旗| 嘉定区| 无为县| 辽宁省| 宜川县| 高碑店市| 西乌珠穆沁旗| 饶阳县| 新田县| 垣曲县| 德格县| 辰溪县|