国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次,處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果,再次證明GenScript 有能力幫助業內科學家Make research easy.

Natural naphthoquinones isolated from Lithospermum erythrorhizon suppress dextran sulfate sodium-induced murine experimental colitis

biorxiv. 2019; 
Wenxue?Sun, ?Hongwei?Han, ?Zhaoyue?Wang, ?Zhongling?Wen, ?Minkai?Yang, ?Yinsong?Wang, ?Jiangyan?Fu, ?Lu?Feng, ?Xinhong?Xu, ?Tongming?Yin, ?Xiaoming?Wang, ?Guihua?Lu, ?Jinliang?Qi, ?Hongyan?Lin, ??View Yonghua?Yang
Products/Services Used Details Operation
Recombinant Proteins All of them were characterized by?13C NMR,?1H NMR, melting properties and MS analysis, which were exactly accord with the structure described (SI Appendix). DSS (white powder; CAS NO. 9011-18-1; LOT: Q6182; M.W. = 36000 – 50000 Da) was purchased from MP Biomedicals (Shanghai, China). Mesalazine (#A600043-0050; CAS NO. 89-57-6; LOT: B326BA1390) was purchased from Sigma-Aldrich (Shanghai, China). Murine TNF-α (#ab208348), IL-1β (#ab197742), IL-6 (#ab100712), IL-10 (#ab108870) Elisa assay kits were purchased from Abcam (Cambridge, England). COX-2 (#SBJ-M0847), iNOS (#SBJ-M0041) and MPO (#SBJ-M0329) Elisa assay kits were ordered from Nanjing SenBeiJia Biological Technology Co., Ltd., (Nanjing, China). Primers were purchased from Genscript (Nanjing, China). All molecular docking results were in strict accordance with operation specification of Discovery Studio 3.5. The docking calculation of mesalazine, shikonin and its derivatives was showed in S1 Table. Get A Quote

摘要

The purpose of this study was to explore the effects of natural shikonin and its derivatives on mice experimental colitis induced by dextran sulfate sodium, and to investigate the underlying mechanisms in?vivo. Our results suggested that, intragastric administration of single compound like shikonin and its derivatives contributed to attenuating symptoms of malignant induced by DSS. Meanwhile, shikonin or its derivatives could also remarkably reduce the disease activity index and histopathological scores, suppress the levels of pro-inflammatory cytokines (including IL-6, IL-1β and TNF-α), while increase that of inflammatory cytokine IL-10 in serum. Additionally, both shikonin and alkanin were found to restrai... More

關鍵詞

              主站蜘蛛池模板: 应城市| 韶山市| 高雄市| 津南区| 保靖县| 英山县| 栾城县| 抚远县| 漳平市| 兴和县| 长岛县| 宜宾县| 莱西市| 阳新县| 英德市| 江源县| 内江市| 阿克苏市| 石嘴山市| 休宁县| 阳东县| 西昌市| 基隆市| 古蔺县| 安庆市| 金昌市| 中宁县| 资阳市| 黔西| 宁明县| 巴东县| 白山市| 临潭县| 封丘县| 夏河县| 策勒县| 三江| 无锡市| 上杭县| 平阳县| 盐津县|