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Characterization of genital chlamydia trachomatis infection among women attending infertility and gynecology clinics in Hunan, China

BMC Infect Dis. 2024-04; 
Qianting Zhou, Jiayan Li, Lipei Luo, Shuling Min, Li Wang, Lixiu Peng, Yinglan Hou, Ping He, Song He, Shixing Tang, Hongliang Chen
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Proteins, Expression, Isolation and Analysis … The cell lysates containing the Nluc-pgp3 fusion protein expressed in HeLa cells were … The 96-well white microplate were coated with 50 μL/well Protein G (5 mg/ml; Genscript, Nanjing, … Get A Quote

摘要

background: Genital infection with Chlamydia trachomatis (C. trachomatis) is a major public health issue worldwide. It can lead to cervicitis, urethritis, and infertility. This study was conducted to determine the characteristics of genital C. trachomatis infection among women attending to the infertility and gynecology clinics. methods: Endocervical swabs were collected from 8,221 women for C. trachomatis nucleotide screening and genotyping, while serum samples were collected for C. trachomatis pgp3 antibody determination using luciferase immunosorbent assays. results: High C. trachomatis DNA prevalence (3.76%) and seroprevalence (47.46%) rates were found, with genotype E (27.5%) being the most prevalent. C. t... More

關(guān)鍵詞

Chlamydia trachomatis, Cervical intraepithelial neoplasia, Genotype, Luciferase immunosorbent assays, Seroprevalence
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