国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次,處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果,再次證明GenScript 有能力幫助業內科學家Make research easy.

Engineering minimal tissue inhibitors of metalloproteinase targeting MMPs via gene shuffling and yeast surface display

Protein Sci. 2023-12; 
Arman Hosseini, Sachin Kumar, Kyle Hedin, Maryam Raeeszadeh-Sarmazdeh
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis … TIMP expression was measured by labeling with mouse anti c-myc (clone 9e10) antibody (GenScript) with a final concentration of 5 μg/mL for 30 min on ice, and bMMP3 protein was … Get A Quote

摘要

Overexpression of specific matrix metalloproteinases (MMPs) has a key role in development of several diseases, such as cancer, neurological disorders, and cardiovascular diseases due to their critical role in degradation and remodeling of the extracellular matrix (ECM). Tissue inhibitors of metalloproteinases (TIMPs), a family of four in humans, are endogenous inhibitors of MMPs. TIMPs have a high level of sequence and structure homology, with a broad range of binding and inhibition to the family of MMPs. It is important to identify the key motifs of TIMPs responsible for inhibition of MMPs to develop?efficient therapeutics targeting specific MMPs. We used DNA shuffling between the human TIMP family to generat... More

關鍵詞

DNA shuffling, directed evolution, matrix metalloproteinase, molecular dynamics simulations, protein docking, protein engineering, tissue inhibitor of metalloproteinase, yeast surface display
              主站蜘蛛池模板: 江油市| 广元市| 玛多县| 天津市| 伊川县| 涿州市| 肇源县| 辉南县| 肥乡县| 桑日县| 洛阳市| 巨鹿县| 休宁县| 博湖县| 汉川市| 离岛区| 巴里| 澜沧| 河池市| 中方县| 呼玛县| 噶尔县| 濉溪县| 开原市| 玉环县| 湖北省| 涞水县| 玛沁县| 达尔| 鄂温| 绥江县| 福海县| 广东省| 赣榆县| 区。| 深圳市| 华亭县| 孟津县| 渝北区| 太谷县| 新安县|