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The putative role of the epipeptide EpeX in intra-species competition

Microbiology (Reading). 2023-06; 
Margarita Kalamara, James Abbott, Tetyana Sukhodub, Cait MacPhee, Nicola R Stanley-Wall
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Proteins, Expression, Isolation and Analysis … For construction of pNW2315 the required fragment was synthesised by GenScript and inserted into the pCC1 vector. The construct sequence can be found in Table S1. Strains with the … Get A Quote

摘要

Bacteria engage in competitive interactions with neighbours that can either be of the same or different species. Multiple mechanisms are deployed to ensure the desired outcome and one tactic commonly implemented is the production of specialised metabolites. The Gram-positive bacterium uses specialized metabolites as part of its intra-species competition determinants to differentiate between kin and non-kin isolates. It is, however, unknown if the collection of specialized metabolites defines competitive fitness when the two isolates start as a close, interwoven community that grows into a densely packed colony biofilm. Moreover, the identity of specialized metabolites that have an active role in defining the o... More

關(guān)鍵詞

Bacillus subtilis, EpeX, biofilm, epipeptide, kin discrimination
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