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Characterization, mRNA expression profile, subcellular distribution and association analysis with piglet diarrhea of porcine matrix metallopeptidase 7 (pMMP7)

Gene. 2022-02; 
Buyue Niu, Lu Liu, Zhihua Chen, Mingxing Kou, Xiuqin Yang, Yuan Sun, Shengwei Di, Xibiao Wang, Jiancheng Cai, Dongchun Guo
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Protein Tools … among tissues. 2.4. Subcellular distribution. PSORT II (https://www.genscript.com/psort. html) was used to predict the intracellular distribution of pMMP7. To?… Get A Quote

摘要

Matrix metalloproteinase 7 (MMP7) is involved in the degradation of extracellular matrix in disease processes and therefore plays an important role in host disease resistance/susceptibility. To better understanding the effects of porcine MMP7 (pMMP7) on piglets diarrhea trait, we characterized pMMP7 gene, identified genetic variations in pMMP7 and explored the relationship between pMMP7 polymorphisms and piglets diarrhea in Min pig and Landrace populations. The complete coding sequence of pMMP7 is 804?bp encoding a protein of 267 amino acids. Sequence alignment showed that the identity between pMMP7 and human MMP7 was approximately 80%. The expression of pMMP7 in the gut of healthy piglets were weak and the di... More

關(guān)鍵詞

Genetic variations, MMP7, Porcine, Subcellular distribution, mRNA Expression
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