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Physical evidence on desmin-lamin B interaction

Cytoskeleton (Hoboken). 2021-01; 
Ecem Kural-Mang?t, Pervin Rukiye Din?er
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Recombinant Proteins … Please cite this article as Kural Mangt,et al., (2021), Physical Evidence on Desmin-Lamin B Interaction.Cytoskeleton, doi: 10.1002/cm.21651 ? 2021 Wiley Periodicals, Inc?… GenScript, and Maison et al.,1997), and performed a co-IP experiment with known interacting?… Get A Quote

摘要

Desmin is a muscle specific intermediate filament protein located in cytoplasm. Lamin B, on the other hand, is a nuclear intermediate filament protein. There are studies suggesting a possible interaction between desmin and lamin B yet there is no physical evidence. In the present study, we have shown for the first time a physical interaction between desmin and lamin B via reciprocal co-immunoprecipitation from muscle tissue of wild type AB zebrafish (Danio rerio, Hamilton). The interaction between desmin and lamin B might be a lead on a novel nucleocytoplasmic communication network.

關鍵詞

desmin, immunoprecipitation, lamin B, muscle, zebrafish
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