国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務(wù)及產(chǎn)品已被Cell, Nature, Science, PNAS等1300多家生物醫(yī)藥類雜志引用近萬次,處于行業(yè)領(lǐng)先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構(gòu)使用GenScript的基因合成、多肽服務(wù)、抗體服務(wù)和蛋白服務(wù)等成功地發(fā)表科研成果,再次證明GenScript 有能力幫助業(yè)內(nèi)科學家Make research easy.

TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA

Nucleic Acids Res. 2021-12; 
Parminder Kaur, Ryan Barnes, Hai Pan, Ariana C Detwiler, Ming Liu, Chelsea Mahn, Jonathan Hall, Zach Messenger, Changjiang You, Jacob Piehler, Robert C Smart, Robert Riehn, Patricia L Opresko, Hong Wang
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis … HA-TIN2L proteins were further estab- lished by the western Blot analysis using the HA antibody (GenScript A00168) and?… The first round of PEGylation was performed using mPEG-SVA (succinimidyl valeric acid PEG, MW 5000, 10 mg, Laysan?… 4 Nucleic Acids Research, 2021?… Get A Quote

摘要

The telomere specific shelterin complex, which includes TRF1, TRF2, RAP1, TIN2, TPP1 and POT1, prevents spurious recognition of telomeres as double-strand DNA breaks and regulates telomerase and DNA repair activities at telomeres. TIN2 is a key component of the shelterin complex that directly interacts with TRF1, TRF2 and TPP1. In vivo, the large majority of TRF1 and TRF2 are in complex with TIN2 but without TPP1 and POT1. Since knockdown of TIN2 also removes TRF1 and TRF2 from telomeres, previous cell-based assays only provide information on downstream effects after the loss of TRF1/TRF2 and TIN2. Here, we investigated DNA structures promoted by TRF2-TIN2 using single-molecule imaging platforms, including trac... More

關(guān)鍵詞

              主站蜘蛛池模板: 永顺县| 光泽县| 松潘县| 黔南| 汉阴县| 叙永县| 贡嘎县| 当阳市| 济宁市| 印江| 蒙阴县| 红安县| 内乡县| 大埔区| 临沧市| 南木林县| 阳谷县| 南昌县| 太仓市| 阿图什市| 海宁市| 新郑市| 垣曲县| 汉沽区| 彩票| 马尔康县| 海口市| 仪陇县| 增城市| 马边| 大田县| 辛集市| 新野县| 虞城县| 南投县| 靖宇县| 宿迁市| 邓州市| 江源县| 波密县| 正阳县|