国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次,處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果,再次證明GenScript 有能力幫助業內科學家Make research easy.

Macrophage Migration Inhibitory Factor Acts as the Potential Target of a Newly Synthesized Compound, 1-(9'-methyl-3'-carbazole)-3, 4-dihydro-β-carboline.

Sci Rep. 2019-02; 
KoPin-Hao,ShenYa-Ching,MuruganKaliyappan,HuangChiung-Wei,SivakumarGovindan,PalPinki,LiaoChia-Ching,LuoKai-Shin,ChuangEric Y,TsaiMong-Hsun,LaiLiang-C
Products/Services Used Details Operation
Recombinant Proteins The hydrogen-deuterium exchange (HDX) of MIF recombinant human protein (GenScript, NJ, USA) was measured in the presence and absence of MCDC. Get A Quote

摘要

For a newly synthesized compound, identifying its target protein is a slow but pivotal step toward understand its pharmacologic mechanism. In this study, we systemically synthesized novel manzamine derivatives and chose 1-(9'-methyl-3'-carbazole)-3, 4-dihydro-β-carboline (MCDC) as an example to identify its target protein and function. MCDC had potent toxicity against several cancer cells. To identify its target protein, we first used a docking screen to predict macrophage migration inhibitory factor (MIF) as the potential target. Biochemical experiments, including mutation analysis and hydrogen-deuterium exchange assays, validated the binding of MCDC to MIF. Furthermore, MCDC was shown by microa... More

關鍵詞

              主站蜘蛛池模板: 涿鹿县| 庐江县| 惠东县| 梅河口市| 华亭县| 鱼台县| 吐鲁番市| 嘉善县| 工布江达县| 洛阳市| 怀柔区| 富平县| 新平| 习水县| 新邵县| 邹城市| 玛多县| 正阳县| 兴业县| 丹巴县| 巴林左旗| 惠安县| 开江县| 承德县| 博白县| 金平| 庆元县| 平邑县| 邳州市| 秭归县| 永登县| 汝阳县| 德州市| 赤壁市| 枞阳县| 娄烦县| 平陆县| 亚东县| 湘西| 鄱阳县| 客服|