PD-1 (2E5), mAb, Mouse

Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.

產品編號	V02201
規格	100 μg:詢價 1 mg:詢價 10 mg:詢價 100 mg:詢價大單詢價
數量
價格	詢價


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Description

Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.

產品概述

Subclass	IgG1
Host Species	Mouse
Conjugation	Unconjugated
Antigen Species	Human

產品屬性

Production	Cultured in vitro under conditions free from animal-derived components
Purification	Protein A/G affinity column
Formulation	1) PBS, pH 7.4, containing 0.03% Proclin 300 2) 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300 * *: For new batch since 09/01/2018, please refer to COA.
Concentration	≥2mg/ml
Clone ID	2E5
Storage	For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

應用指導

IHC

技術背景

Target Background

Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.

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PD-1 (2E5), mAb, Mouse

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