国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務(wù)及產(chǎn)品已被Cell, Nature, Science, PNAS等1300多家生物醫(yī)藥類雜志引用近萬次,處于行業(yè)領(lǐng)先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學(xué)等約400家全球著名機(jī)構(gòu)使用GenScript的基因合成、多肽服務(wù)、抗體服務(wù)和蛋白服務(wù)等成功地發(fā)表科研成果,再次證明GenScript 有能力幫助業(yè)內(nèi)科學(xué)家Make research easy.

Molecular mechanisms of the viral encoded chaperone 100K in capsid folding and assembly of adenovirus

Nat Commun. 2025-04; 
Haining Li , Luyuan Shao , Zhe Liu , Qi Liu , Ye Xiang
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis The eluted sample was applied to the anti-Flag resin (GenScript, Product L00432). Get A Quote

摘要

Adenovirus is an icosahedral, non-enveloped DNA virus that infects humans and other animals. The capsid of adenovirus is mainly assembled by the major capsid protein hexon. Folding and assembly of hexon require the viral encoded chaperone 100K, of which the detailed structure and chaperoning mechanism remain unknown. Here, we report the cryoEM structure of 100K in complex with a pre-mature hexon trimer. The structure shows that 100K dimers bind to the bottom double jelly-roll domains of the pre-mature hexon, mainly through a hook-like domain and a loop extruded from the dimerization domain. Additionally, a groove formed at the dimerization interface of 100K accommodates the N-terminal fragment 49-53 of an adjac... More

關(guān)鍵詞

              主站蜘蛛池模板: 秦安县| 藁城市| 昌都县| 合江县| 黔江区| 芮城县| 肥西县| 灌云县| 武冈市| 宜城市| 新民市| 田阳县| 屯昌县| 波密县| 收藏| 外汇| 介休市| 元江| 蕲春县| 甘德县| 义乌市| 弋阳县| 新乡市| 昌宁县| 屏东县| 绍兴市| 额尔古纳市| 商水县| 杨浦区| 乐昌市| 德令哈市| 突泉县| 日喀则市| 宝兴县| 台东县| 衡阳县| 石河子市| 蓝田县| 宜良县| 平乡县| 香格里拉县|