国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次,處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果,再次證明GenScript 有能力幫助業內科學家Make research easy.

Podocyte Pathogenic Bone Morphogenetic Protein-2 Pathway and Immune Cell Behaviors in Primary Membranous Nephropathy

Adv Sci (Weinh). 2024-05; 
Anxiang Cai, Yiwei Meng, Hang Zhou, Hong Cai, Xinghua Shao, Qin Wang, Yao Xu, Yin Zhou, Wenyan Zhou, Luonan Chen, Shan Mou
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis … concentration was measured using a BCA assay, and equal amounts of protein were loaded on PAGE 4%–20% gradient gels (GenScript) and transferred to PVDF membranes (Millipore… Get A Quote

摘要

Primary membranous nephropathy (PMN) is one of the leading causes of end-stage renal disease, and the most frequent cause of massive proteinuria in nondiabetic adults, resulting in fatal complications. However, the underlying pathomechanisms of PMN remain largely unclear. Here, single-cell RNA sequencing is employed to analyze kidney biopsies from eleven PMN patients and seven healthy subjects. Profiling 44?060 cells from patients allowed us to characterize the cellular composition and cell-type-specific gene expression in the PMN kidney. The complement-induced BMP2/pSMAD1/COL4 pathway is identified as the pathogenic pathway in podocytes, bridging two key events, i.e., complement system activation and glomerul... More

關鍵詞

bone morphogenetic protein 2, chronic kidney disease, podocyte, primary membranous nephropathy, proteinuria, renal immune cell, single‐cell RNA sequencing
              主站蜘蛛池模板: 赤峰市| 墨玉县| 南宁市| 陆川县| 板桥市| 嘉定区| 绥芬河市| 无为县| 高清| 府谷县| 吕梁市| 定日县| 马山县| 彰武县| 龙州县| 灌南县| 弋阳县| 郯城县| 黄浦区| 大方县| 石嘴山市| 武冈市| 济阳县| 饶阳县| 海伦市| 泽州县| 高要市| 太和县| 绥宁县| 阿坝县| 海林市| 齐齐哈尔市| 临颍县| 南江县| 洞口县| 漳平市| 古交市| 武清区| 桂平市| 乳山市| 吴桥县|