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Metabolic engineering of Zymomonas mobilis for 2，3-butanediol production from lignocellulosic biomass sugars.

Biotechnol Biofuels. 2016;

YangShihui，MohagheghiAli，F(xiàn)randenMary Ann，ChouYat-Chen，ChenXiaowen，DoweNancy，HimmelMichael E，Zhan

Products/Services Used	Details	Operation
Codon Optimization	These included one codon-optimized BlAls gene and two versions of the BsAls genes (BsAls1 and BsAls2) with different codon optimization outputs using Genscript’s codon optimization algorithm….Wild-type and codon-optimized versions of three 2,3-BDO biosynthesis pathway genes were synthesized by Genscript (NJ, USA).	Get A Quote

摘要

To develop pathways for advanced biofuel production， and to understand the impact of host metabolism and environmental conditions on heterologous pathway engineering for economic advanced biofuels production from biomass， we seek to redirect the carbon flow of the model ethanologen Zymomonas mobilis to produce desirable hydrocarbon intermediate 2，3-butanediol (2，3-BDO). 2，3-BDO is a bulk chemical building block， and can be upgraded in high yields to gasoline， diesel， and jet fuel.