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Kinetic and Structural Characterization of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors

Authors: Kayla Glockzin, Kathleen M Meneely, Ryan Hughes, Sean W Maatouk, Grace E Pi?a, Kajitha Suthagar, Keith Clinch, Joshua N Buckler, Audrey L Lamb, Peter C Tyler, Thomas D Meek, Ardala Katzfuss

Journal: Biochemistry

PubMed ID: 37418678

Doi: 10.1021/acs.biochem.3c00116

Products & Services: Proteins, Expression, Isolation and Analysis

Role and neural regulation of clock genes in the rat pineal gland: Clock modulates amplitude of rhythmic expression of Aanat encoding the melatonin-producing enzyme

Authors: Aurea S Blancas-Velazquez, Tenna Bering, Signe Bille, Martin F Rath

Journal: J Pineal Res

PubMed ID: 37349875

Doi: 10.1111/jpi.12893

Products & Services: Proteins, Expression, Isolation and Analysis

A neural cell adhesion molecule from oyster Crassostrea gigas: Molecular identification and immune functional characterization

Authors: Xue Qiao, Conghui Liu, Weilin Wang, Chuanyan Yang, Meijia Li, Qilin Yi, Ning Kong, Limei Qiu, Xiyang Liu, Lingling Wang, Linsheng Song

Journal: Int J Biol Macromol

PubMed ID: 37429340

Doi: 10.1016/j.ijbiomac.2023.125756

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering the HK97 virus-like particle as a nanoplatform for biotechnology applications

Authors: Michael D Woods, Matthew Cali, Bubacarr Ceesay, Shandis Fancher, Gaini Ibrasheva, Suefian Kandeel, Manon Nassar, Ali Azghani, Brent Bill, Dustin P Patterson

Journal: J Mater Chem B

PubMed ID: 37345352

Doi: 10.1039/d3tb00318c

Products & Services: Proteins, Expression, Isolation and Analysis

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice

Authors: Nana Li, Junjie Yu, Meiyang Zhou, Fanyi Qiu, Xiao Wang, Zhengpin Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 37451217

Doi: 10.1016/j.bbrc.2023.07.013

Products & Services: Proteins, Expression, Isolation and Analysis

Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery

Authors: Natalie S Wallace, John E Gadbery, Cameron I Cohen, Amy K Kendall, Lauren P Jackson

Journal: biorxiv

PubMed ID: 37502979

Doi: 10.1101/2023.07.18.549521

Products & Services: Proteins, Expression, Isolation and Analysis

Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results

Authors: Raffit Hassan, Marcus Butler, Roisin E O'Cearbhaill, David Y Oh, Melissa Johnson, Kevin Zikaras, Munisha Smalley, Michael Ross, Janos L Tanyi, Azam Ghafoor, Nirali N Shah, Babak Saboury, Liang Cao, Alfonso Quintás-Cardama, David Hong

Journal: Nat Med

PubMed ID: 37501016

Doi: 10.1038/s41591-023-02452-y

Products & Services: Proteins, Expression, Isolation and Analysis

Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis

Authors: Aleksandra W Debowski, Nicole M Bzdyl, David R Thomas, Nichollas E Scott, Christopher H Jenkins, Jua Iwasaki, Emily A Kibble, Chen Ai Khoo, Nicolas J Scheuplein, Pamela M Seibel, Theresa Lohr, Georgie Metters, Charles S Bond, Isobel H Norville, Keith A Stubbs, Nicholas J Harmer, Ulrike Holzgrabe, Hayley J Newton, Mitali Sarkar-Tyson

Journal: PLoS Pathog

PubMed ID: 37399210

Doi: 10.1371/journal.ppat.1011491

Products & Services: Proteins, Expression, Isolation and Analysis

The combination of osimertinib with Raf inhibitor overcomes osimertinib resistance induced by KRAS amplification in EGFR-mutated lung cancer cells

Authors: Tae-Gul Lee, Hye-Min Kang, Seo Yun Kim, Hye-Ryoun Kim, Cheol Hyeon Kim

Journal: Exp Cell Res

PubMed ID: 37442265

Doi: 10.1016/j.yexcr.2023.113722

Products & Services: Proteins, Expression, Isolation and Analysis

Combined Inhibition of the TGF-β1/Smad Pathway by and to Reduce Inflammation and Fibrosis in Primary Sclerosing Cholangitis

Authors: Yu Shen, Baorong Jiang, Chenchen Zhang, Qian Wu, Lei Li, Ping Jiang