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Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform

Authors: Ngan T B Nguyen, Hau Wan Leung, Kuin Tian Pang, Shi Jie Tay, Ian Walsh, Andre B H Choo, Yuansheng Yang

Journal: Sci Rep

PubMed ID: 37731040

Doi: 10.1038/s41598-023-42925-1

Products & Services: Proteins, Expression, Isolation and Analysis

Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

Authors: Matteo Righi, Isaac Gannon, Matthew Robson, Saket Srivastava, Evangelia Kokalaki, Thomas Grothier, Francesco Nannini, Christopher Allen, Yuchen V Bai, James Sillibourne, Shaun Cordoba, Simon Thomas, Martin Pule

Journal: Cancer Immunol Res

PubMed ID: 37352396

Doi: 10.1158/2326-6066.CIR-22-0640

Products & Services: Proteins, Expression, Isolation and Analysis

Soluble CD4 and low molecular weight CD4-mimetic compounds sensitize cells to be killed by anti-HIV cytotoxic immunoconjugates

Authors: Seth H Pincus, Megan Stackhouse, Connie Watt, Kelli Ober, Frances M Cole, Hung-Ching Chen, Amos B Smith Iii, Tami Peters

Journal: J Virol

PubMed ID: 37772823

Doi: 10.1128/jvi.01154-23

Products & Services: Proteins, Expression, Isolation and Analysis

Phosphatidylinositol-specific phospholipase C can decrease Müller cell viability and suppress its phagocytic activity by modulating PI3K/AKT signaling pathway

Authors: Bianjin Sun, Shudan Lin, Mengmeng Zheng, Beijia Zheng, Liping Mao, Yunfeng Gu, Jiabei Cai, Yiran Dai, Meiqin Zheng, Yongliang Lou

Journal: Can J Microbiol

PubMed ID: 37672795

Doi: 10.1139/cjm-2023-0044

Products & Services: Proteins, Expression, Isolation and Analysis

AXL Inhibition Improves the Antitumor Activity of Chimeric Antigen Receptor T Cells

Authors: R Leo Sakemura, Mehrdad Hefazi, Michelle J Cox, Elizabeth L Siegler, Sutapa Sinha, Michael J Hansen, Carli M Stewart, Jennifer M Feigin, Claudia Manriquez Roman, Kendall J Schick, Ismail Can, Erin E Tapper, Paulina Horvei, Mohamad M Adada, Evandro D Bezerra, Lionel Aurelien Kankeu Fonkoua, Michael W Ruff, Cynthia L Forsman, Wendy K Nevala, Justin C Boysen, Renee C Tschumper, Cory L Grand, Kameswara R Kuchimanchi, Lars Mouritsen, Jason M Foulks, Steven L Warner, Timothy G Call, Sameer A Parikh, Wei Ding, Neil E Kay, Saad S Kenderian

Journal: Cancer Immunol Res

PubMed ID: 37378662

Doi: 10.1158/2326-6066.CIR-22-0254

Products & Services: Proteins, Expression, Isolation and Analysis

Nuclear factor E2-associated factor 2 and musculoaponeurotic fibrosarcoma K mediate regulation glutathione peroxidase of Cristaria plicata after microcystin-induced oxidative stress

Authors: Xinying Cao, Jinhua An, Shanshan Zhu, Maolin Feng, Yang Gang, Chungen Wen, Baoqing Hu

Journal: Comp Biochem Physiol C Toxicol Pharmacol

PubMed ID: 37689170

Doi: 10.1016/j.cbpc.2023.109742

Products & Services: Proteins, Expression, Isolation and Analysis

DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress

Authors: Xu Lin, Ye-Han Liu, Huan-Qi Zhang, Lin-Wen Wu, Qi Li, Jun Deng, Qingyi Zhang, Yuhong Yang, Chong Zhang, Yang-Ling Li, Jian Hu

Journal: Cancer Cell Int

PubMed ID: 37742009

Doi: 10.1186/s12935-023-03047-w

Products & Services: Proteins, Expression, Isolation and Analysis

Omicron variant neutralizing antibodies following BNT162b2 BA4/5 versus mRNA-1273 BA1 bivalent vaccination in patients with end-stage kidney disease

Authors: Kevin Yau, Alexandra Kurtesi, Freda Qi, Melanie Delgado-Brand, Tulunay R Tursun, Queenie Hu, Miten Dhruve, Christopher Kandel, Omosomi Enilama, Adeera Levin, Yidi Jiang, W Rod Hardy, Darren A Yuen, Jeffrey Perl, Christopher T Chan, Jerome A Leis, Matthew J Oliver, Karen Colwill, Anne-Claude Gingras, Michelle A Hladunewich

Journal: Nat Commun

PubMed ID: 37758707

Doi: 10.1038/s41467-023-41678-9

Products & Services: Proteins, Expression, Isolation and Analysis

A real-time analysis of protein transport via the twin arginine translocation pathway in response to different components of the protonmotive force

Authors: Wenjie Zhou, Binhan Hao, Terry M Bricker, Steven M Theg

Journal: J Biol Chem

PubMed ID: 37742925

Doi: 10.1016/j.jbc.2023.105286

Products & Services: Proteins, Expression, Isolation and Analysis

Protective efficacy of a universal influenza mRNA vaccine against the challenge of H1 and H5 influenza A viruses in mice

Authors: Yulei Li, Xi Wang, Xi Zeng, Wenbo Ren, Pu Liao, Baoli Zhu