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The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis
Authors: Jennilee M Davidson, Sharlynn S L Wu, Stephanie L Rayner, Flora Cheng, Kimberley Duncan, Carlo Russo, Michelle Newbery, Kunjie Ding, Natalie M Scherer, Rachelle Balez, Alberto García-Redondo, Alberto Rábano, Livia Rosa-Fernandes, Lezanne Ooi, Kelly L Williams, Marco Morsch, Ian P Blair, Antonio Di Ieva, Shu Yang, Roger S Chung, Albert Lee
Journal: Mol Neurobiol
PubMed ID: 37243816
Doi: 10.1007/s12035-023-03355-2
saRNA vaccine expressing membrane-anchored RBD elicits broad and durable immunity against SARS-CoV-2 variants of concern
Authors: Mai Komori, Takuto Nogimori, Amber L Morey, Takashi Sekida, Keiko Ishimoto, Matthew R Hassett, Yuji Masuta, Hirotaka Ode, Tomokazu Tamura, Rigel Suzuki, Jeff Alexander, Yasutoshi Kido, Kenta Matsuda, Takasuke Fukuhara, Yasumasa Iwatani, Takuya Yamamoto, Jonathan F Smith, Wataru Akahata
Journal: Nat Commun
PubMed ID: 37208330
Doi: 10.1038/s41467-023-38457-x
Leveraging a Structural Blueprint to Rationally Engineer the Rieske Oxygenase TsaM
Authors: Jiayi Tian, Alejandro Arcadio Garcia, Patrick H Donnan, Jennifer Bridwell-Rabb
Journal: Biochemistry
PubMed ID: 37188334
Doi: 10.1021/acs.biochem.3c00150
Antibody blockade of Jagged1 attenuates choroidal neovascularization
Authors: Torleif Tollefsrud Gj?lberg, Jonas Aakre Wik, Hanna Johannessen, Stig Krüger, Nicola Bassi, Panagiotis F Christopoulos, Malin Bern, Stian Foss, Goran Petrovski, Morten C Moe, Guttorm Haraldsen, Johanna Hol Fosse, Bj?rn Steen Sk?lhegg, Jan Terje Andersen, Eirik Sundlis?ter
Journal: Nat Commun
PubMed ID: 37253747
Doi: 10.1038/s41467-023-38563-w
Preparation of magnetic polyacrylamide hydrogel with chitosan for immobilization of glutamate decarboxylase to produce γ-aminobutyric acid
Authors: Jianjun Wang, Luyao Wang, Chengli Yang, Yihui Zhu, Ziqian Chen, Guanya He, Kaishun Hu, Kaixuan Liu, Beibei Fang, Dali Li, Ruofu Shi
Journal: Prep Biochem Biotechnol
PubMed ID: 37184437
Doi: 10.1080/10826068.2023.2209884
Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1
Authors: Laura Hakanp??, Amr Abouelezz, An-Sofie Lenaerts, Seyda Culfa, Michael Algie, Jenny B?rlund, Pekka Katajisto, Harvey McMahon, Leonardo Almeida-Souza
Journal: J Cell Biol
PubMed ID: 37233325
Doi: 10.1083/jcb.202303107
JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding
Authors: Carlos G Ardanaz, Amaia Ezkurdia, Arantza Bejarano, Beatriz Echarte, Cristian Smerdou, Eva Martisova, Iván Martínez-Valbuena, María-Rosario Luquin, María J Ramírez, Maite Solas
Journal: ACS Chem Neurosci
PubMed ID: 37236204
Doi: 10.1021/acschemneuro.3c00092
CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage
Authors: Elizabeth J Lawrence, Saptarshi Chatterjee, Marija Zanic
Journal: J Cell Biol
PubMed ID: 37184584
Doi: 10.1083/jcb.202107027
Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent
Authors: Xu Hou, Taylor Hsuan-Yu Chen, Shunsuke Koga, Jenny M Bredenberg, Ayman H Faroqi, Marion Delenclos, Guojun Bu, Zbigniew K Wszolek, Jonathan A Carr, Owen A Ross, Pamela J McLean, Melissa E Murray, Dennis W Dickson, Fabienne C Fiesel, Wolfdieter Springer
Journal: Brain Pathol
PubMed ID: 37259617
Doi: 10.1111/bpa.13175
Single point mutations at the S129 residue of α-synuclein and their effect on structure, aggregation, and neurotoxicity
Authors: Esha Pandit, Lopamudra Das, Anoy Kumar Das, Sandip Dolui, Saumen Saha, Uttam Pal, Animesh Mondal, Joydeep Chowdhury, Subhas C Biswas, Nakul C Maiti
Journal: Front Chem
PubMed ID: 37304685
Doi: 10.3389/fchem.2023.1145877

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