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Respiratory syncytial virus glycoprotein G impedes CX3CR1-activation by CX3CL1 and monocyte function

Authors: Robert Meineke, Ayse Agac, Marie-Christin Knittler, Martin Ludlow, Albert D. M. E. Osterhaus & Guus F. Rimmelzwaan

Journal: npj viruses

Doi: doi.org/10.1038/s44298-024-00075-9

Products & Services: Gene Synthesis Mutagenesis Services

Reduced cross-protective potential of Omicron compared to ancestral SARS-CoV-2 spike vaccines against potentially zoonotic coronaviruses.

Authors: Tyler M. Renner, Matthew Stuible, Brian Cass, Sylvie Perret, Julie Guimond, Simon Lord-Dufour, Michael J. McCluskie, Yves Durocher & Bassel Akache

Journal: npj Viruses

Doi: 10.1038/s44298-024-00067-9

Products & Services: Gene Synthesis

Chemoenzymatic Synthesis of the Cyclopiane Family of Diterpenoid Natural Products

Authors: Zhengren Xu, Tao Wang, Jiasheng Zou, Kaibiao Wang, Yuanning Liu, Shouqi Zhang, Yao Kong

Journal: Angew Chem Int Ed Engl

PubMed ID: 39601390

Doi: 10.1002/anie.202419092

Products & Services: Gene Synthesis

Expression and functional study of DNA polymerases from Psychrobacillus sp. BL-248-WT-3 and FJAT-21963

Authors: Yaping Sun , Danny Hsu Ko , Jie Gao , Kang Fu , Yuanchen Mao , Yun He , Hui Tian

Journal: Front Microbiol

PubMed ID: 39633807

Doi: doi.org/10.3389/fmicb.2024.1501020

Products & Services: Gene Synthesis

An Isopentenol Utilization Pathway-Based “Deuterium-Scanning“Method for Mechanistic Investigations of Terpene Cyclases

Authors: Shouqi Zhang, Kaibiao Wang,Yuanning Liu, Tao Wang, Yao Kong, Pengcheng Zhang, Bo Zhang, Min Yin, Guohui Pan, and Zhengren Xu

Journal: ACS catalysis

Doi: 10.1021/acscatal.4c05811

Products & Services: Gene Synthesis

Bivalent CD47 immunotoxin for targeted therapy of T-cell acute lymphoblastic leukemia

Authors: Jihong Ma , Zhaohui Wang , Danielle Mintzlaff , Huiping Zhang , Rashmi Ramakrishna , Eduardo Davila , Matthew T Witkowski , M Scott Lucia , Marc S Schwartz , Elizabeth A Pomfret , David W Mathes , Zhirui Wang

Journal: Blood

PubMed ID: 39561285

Doi: 10.1182/blood.2024025277

Products & Services: Gene Synthesis

Split-design approach enhances the therapeutic efficacy of ligand-based CAR-T cells against multiple B-cell malignancies

Authors: Shuhong Li , Licai Shi , Lijun Zhao , Qiaoru Guo , Jun Li , Ze-Lin Liu , Zhi Guo , Yu J Cao

Journal: Nat Commun

PubMed ID: 39528513

Doi: 10.1038/s41467-024-54150-z

Products & Services: Recombinant Proteins Gene Synthesis

Evolutionary insights into the stereoselectivity of imine reductases based on ancestral sequence reconstruction

Authors: Xin-Xin Zhu, Wen-Qing Zheng, Zi-Wei Xia, Xin-Ru Chen, Tian Jin, Xu-Wei Ding, Fei-Fei Chen, Qi Chen, Jian-He Xu, Xu-Dong Kong, Gao-Wei Zheng

Journal: Nat Commun

PubMed ID: 39609402

Doi: 10.1038/s41467-024-54613-3

Products & Services: Gene Synthesis

RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA

Authors: Liying Zhang, Zhiheng Deng, Yunxiang Du, Ziyu Xu, Tianyi Zhang, Zebin Tong, Huasong Ai, Lu-Jun Liang, Lei Liu

Journal: Bioorg Med Chem

PubMed ID: 39580855

Doi: 10.1016/j.bmc.2024.118016

Products & Services: Gene Synthesis Proteins, Expression, Isolation and Analysis

Engineered mRNAs with stable structures minimize double-stranded RNA formation and increase protein expression

Authors: Qianshan Qin , Huayuan Yan , Weixiang Gao , Ruyin Cao , Guopeng Liu , Xiaojing Zhang , Niangang Wang , Wenjie Zuo , Lei Yuan , Peng Gao , Qi Liu

Journal: J Mol Biol

PubMed ID: 39427983

Doi: 10.1016/J.JMB.2024.168822

Products & Services: Gene Synthesis

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