Immobilized SLAMF2 (Mammalian,C-mFc) at 1 μg/ml, 2 μg/ml(100 μl/well) can bind 2B4/CD244 Fc Chimera, Human with EC50=48.56 ng/ml, EC50=75.13 ng/ml when detected by Mouse Anti Human IgG Fc-HRP. Background was subtracted from data points before curve fitting.

2B4/CD244 Fc Chimera, Human

CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4. This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.

產品編號	Z03445
規格	50 μg 100 μg 1 mg 大單詢價
數量
價格	￥960


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產品簡介

Species

Human

Protein Construction

2B4/CD244 (Cys22-Arg221) Accession # Q9BZW8	hFc
N-term	C-term

Purity

> 95% as analyzed by SDS-PAGE

Endotoxin Level

< 1 EU/μg of protein by gel clotting method

Biological Activity

Immobilized SLAMF2 (Mammalian,C-mFc) at 1.0 μg/ml, 2.0 μg/ml(100 μl/well) can bind 2B4/CD244, hFc, Human with EC₅₀=48.56 ng/ml, EC₅₀=75.13 ng/ml when detected by Mouse Anti Human IgG Fc-HRP.

Expression System

HEK 293

Apparent Molecular Weight

~73.6 kDa, on SDS-PAGE under reducing conditions.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

圖例

技術背景

Target Background

Synonyms

NAIL; NKR2B4; Nmrk; SLAMF4; CD244 molecule; CD_antigen: CD244

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

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2B4/CD244 Fc Chimera, Human

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