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Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies

Authors: Anusmita Sahoo, Edgar A Hodge, Celia C LaBranche, Tiffany M Styles, Xiaoying Shen, Narayanaiah Cheedarla, Ayalnesh Shiferaw, Gabriel Ozorowski, Wen-Hsin Lee, Andrew B Ward, Georgia D Tomaras, David C Montefiori, Darrell J Irvine, Kelly K Lee, Rama Rao Amara

Journal: Cell Rep

PubMed ID: 35235790

Doi: 10.1016/j.celrep.2022.110436

Products & Services: Gene Synthesis

Targeting insulin-like growth factor-1 receptor (IGF1R) for brain delivery of biologics

Authors: Wael Alata, Alvaro Yogi, Eric Brunette, Christie E Delaney, Henk van Faassen, Greg Hussack, Umar Iqbal, Kristin Kemmerich, Arsalan S Haqqani, Maria J Moreno, Danica B Stanimirovic

Journal: FASEB J

PubMed ID: 35192204

Doi: 10.1096/fj.202101644R

Products & Services: Gene Synthesis

A toolkit for recombinant production of seven human EGF family growth factors in active conformation

Authors: Arthur Schveitzer Ferreira, Amanda Lopacinski, Michel Batista, Priscila Mazzocchi Hiraiwa, Beatriz Gomes Guimar?es, Nilson Ivo Tonin Zanchin

Journal: Sci Rep

PubMed ID: 35322149

Doi: 10.1038/s41598-022-09060-9

Products & Services: Gene Synthesis

A multi-epitopes tandem antigen for five types of human adenoviruses and its application in development of multivalent IgM immunochromatographic strip test

Authors: Liqiang Zong, Yong Qi, Wei Li, Wanpeng Shen, Jiameng Li, Ruichen Lv, Nianhong Lu, Susu Zhuang, Qiyuan Gui, Dongming Zhou, Yingjia Xu, Zhao Nan, Yuexi Li

Journal: Diagn Microbiol Infect Dis

PubMed ID: 35378470

Doi: 10.1016/j.diagmicrobio.2022.115675

Products & Services: Gene Synthesis

Exogenous Annexin 1 inhibits Th17 cell differentiation induced by anti-TNF treatment via activating FPR2 in DSS-induced colitis

Authors: Xing Liu, Lulu Zhou, Wenjie Xin, Zichun Hua

Journal: Int Immunopharmacol

PubMed ID: 35306282

Doi: 10.1016/j.intimp.2022.108685

Products & Services: Gene Synthesis

The Atypical Chemerin Receptor GPR1 Displays Different Modes of Interaction with β-Arrestins in Humans and Mice with Important Consequences on Subcellular Localization and Trafficking

Authors: Gaetan-Nagim Degroot, Valentin Lepage, Marc Parmentier, Jean-Yves Springael

Journal: Cells

PubMed ID: 35326488

Doi: 10.3390/cells11061037

Products & Services: Gene Synthesis

Ubiquitylation is required for the incorporation of the Notch receptor into intraluminal vesicles to prevent prolonged and ligand-independent activation of the pathway

Authors: Bj?rn Schnute, Hideyuki Shimizu, Marvin Lyga, Martin Baron, Thomas Klein

Journal: BMC Biol

PubMed ID: 35264151

Doi: 10.1186/s12915-022-01245-y

Products & Services: Gene Synthesis

mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice

Authors: Zekun Mu, Kevin Wiehe, Kevin O Saunders, Rory Henderson, Derek W Cain, Robert Parks, Diana Martik, Katayoun Mansouri, Robert J Edwards, Amanda Newman, Xiaozhi Lu, Shi-Mao Xia, Amanda Eaton, Mattia Bonsignori, David Montefiori, Qifeng Han, Sravani Venkatayogi, Tyler Evangelous, Yunfei Wang, Wes Rountree, Bette Korber, Kshitij Wagh, Ying Tam, Christopher Barbosa, S Munir Alam, Wilton B Williams, Ming Tian, Frederick W Alt, Norbert Pardi, Drew Weissman, Barton F Haynes

Journal: Cell Rep

PubMed ID: 35294883

Doi: 10.1016/j.celrep.2022.110514

Products & Services: Gene Synthesis

Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain

Authors: Gang Ye, Bin Liu, Fang Li

Journal: Nat Commun

PubMed ID: 35241675

Doi: 10.1038/s41467-022-28882-9

Products & Services: Gene Synthesis

Understanding desaturation/hydroxylation activity of castor stearoyl Δ9-Desaturase through rational mutagenesis

Authors: Michal Tupec , Martin Culka , Ale? Machara , Stanislav Machácˇek , Daniel Bím , Ale? Svato? , Lubomír Rulí?ek , Iva Pichová

Journal: Elsevier B.V.

Doi: 10.1016/j.csbj.2022.03.010

Products & Services: Gene Synthesis

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