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至今，GenScript的服務(wù)及產(chǎn)品已被Cell, Nature, Science, PNAS等1300多家生物醫(yī)藥類雜志引用近萬次，處于行業(yè)領(lǐng)先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學(xué)等約400家全球著名機構(gòu)使用GenScript的基因合成、多肽服務(wù)、抗體服務(wù)和蛋白服務(wù)等成功地發(fā)表科研成果，再次證明GenScript 有能力幫助業(yè)內(nèi)科學(xué)家Make research easy.

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Purification of an insect juvenile hormone receptor complex enables insights into its post-translational phosphorylation

Authors: Marek Jindra, William J McKinstry, Thomas Nebl, Lenka Bittova, Bin Ren, Jan Shaw, Tram Phan, Louis Lu, Jason K K Low, Joel P Mackay, Lindsay G Sparrow, George O Lovrecz, Ronald J Hill

Journal: J Biol Chem

PubMed ID: 34758356

Doi: 10.1016/j.jbc.2021.101387

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New Role for Radical SAM Enzymes in the Biosynthesis of Thio(seleno)oxazole RiPP Natural Products

Authors: Julia K Lewis, Andrew S Jochimsen, Sarah J Lefave, Anthony P Young, William M Kincannon, Andrew G Roberts, Matthew T Kieber-Emmons, Vahe Bandarian

Journal: Biochemistry

PubMed ID: 34730336

Doi: 10.1021/acs.biochem.1c00469

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In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 in a single ESI-MS spectrum

Authors: Luis Ariel Espinosa, Yassel Ramos, Ivan Andújar, Enso Onill Torres, Gleysin Cabrera, Alejandro Martín, Diamilé Roche, Glay Chinea, Mónica Becquet, Isabel González, Camila Canaán-Haden, Elías Nelson, Gertrudis Rojas, Beatriz Pérez-Massón, Dayana Pérez-Martínez, Tamy Boggiano, Julio Palacio, Sum Lai Lozada Chang, Lourdes Hernández, Kathya Rashida de la Luz Hernández, Saloheimo Markku, Marika Vitikainen, Yury Valdés-Balbín, Darielys Santana-Medero, Daniel G Rivera, Vicente Vérez-Bencomo, Mark Emalfarb, Ronen Tchelet, Gerardo Guillén, Miladys Limonta, Eulogio Pimentel, Marta Ayala, Vladimir Besada, Luis Javier González

Journal: Anal Bioanal Chem

PubMed ID: 34739558

Doi: 10.1007/s00216-021-03721-w

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Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant

Authors: Bassel Akache, Tyler M Renner, Anh Tran, Lise Deschatelets, Renu Dudani, Blair A Harrison, Diana Duque, Julie Haukenfrers, Martin A Rossotti, Francis Gaudreault, Usha D Hemraz, Edmond Lam, Sophie Régnier, Wangxue Chen, Christian Gervais, Matthew Stuible, Lakshmi Krishnan, Yves Durocher, Michael J McCluskie

Journal: Sci Rep

PubMed ID: 34750472

Doi: 10.1038/s41598-021-01363-7

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Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations

Authors: Barbora Novotná, Lucie Holá, Monika Sta?, Ondrej Gutten, Miroslav Smola, Martin Zav?el, Zdeněk Vav?ina, Milo? Budě?ínsky, Radek Liboska, Florian Chevrier, Juraj Dobia?, Evzen Boura, Lubomír Rulí?ek, Gabriel Birku?

Journal: Biochemistry

PubMed ID: 34788017

Doi: 10.1021/acs.biochem.1c00692

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Two C1-oxidizing AA9 lytic polysaccharide monooxygenases from Sordaria brevicollis differ in thermostability, activity, and synergy with cellulase

Authors: Xi Zhang, Kaixiang Chen, Liangkun Long, Shaojun Ding

Journal: Appl Microbiol Biotechnol

PubMed ID: 34748039

Doi: 10.1007/s00253-021-11677-1

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SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II

Authors: Richard King, Zesen Lin, Ginette Balbin-Cuesta, Gregg Myers, Ann Friedman, Guojing Zhu, Beth McGee, Thomas L Saunders, Ryo Kurita, Yukio Nakamura, James Douglas Engel, Pavan Reddy, Rami Khoriaty

Journal: Sci Adv

PubMed ID: 34818036

Doi: 10.1126/sciadv.abj5293

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Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus

Authors: Ebru Destan, Busra Yuksel, Bradley B Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A Francis, Hasan DeMirci

Journal: Sci Rep

PubMed ID: 34819551

Doi: 10.1038/s41598-021-02180-8

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Proteolytic processing of plant proteins by potyvirus NIa proteases

Authors: Huogen Xiao, Etienne Lord, Hélène Sanfa?on

Journal: J Virol

PubMed ID: 34757836

Doi: 10.1128/JVI.01444-21

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Structure of native HIV-1 cores and their interactions with IP6 and CypA

Authors: Tao Ni, Yanan Zhu, Zhengyi Yang, Chaoyi Xu, Yuriy Chaban, Tanya Nesterova, Jiying Ning, Till B?cking, Michael W Parker, Christina Monnie, Jinwoo Ahn, Juan R Perilla, Peijun Zhang

Journal: Sci Adv

PubMed ID: 34797722

Doi: 10.1126/sciadv.abj5715

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