FGF-21, His, Human

FGF-21, also known as fibroblast growth factor-21 and FGFL, is a secreted growth factor belonging to theheparin-binding growth factor family. It is produced by hepatocytes in response to fatty acid stimulation. FGF-21 couples with its co-factor beta-Klotho to signal through FGFR1c and FGFR4. Signal transduction results in insulin-independent uptake of glucose by adipocytes. Clinical administration of FGF-21 induces energy expenditure, fat utilization and lipid excretion.

價格	￥500
產(chǎn)品編號	Z03207
規(guī)格	10 μg 50 μg 1 mg 大單詢價
數(shù)量

產(chǎn)品簡介圖例技術(shù)背景

產(chǎn)品簡介

Species

Human

Protein Construction

FGF-21 (His29-Ser209) Accession # Q9NSA1	Poly-His
N-term	C-term

Purity

> 95% as analyzed by SDS-PAGE

Endotoxin Level

< 0.2 EU/μg of protein by gel clotting method

Biological Activity

ED₅₀ < 0.3 μg/ml, measured in a bioassay using NIH-3T3 cells.

Expression System

CHO

Apparent Molecular Weight

23~25 kDa, on SDS-PAGE under reducing conditions.

Formulation

Lyophilized after extensive dialysis against PBS.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

圖例

技術(shù)背景

Target Background

Synonyms

FGF21; fibroblast growth factor-21; FGFL

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

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FGF-21, His, Human

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