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目錄產品 » 穩定細胞系 » Human Recombinant CTLA4 Stable Cell Line

FACS analysis of CTLA4 expression in CHO-K1/CTLA4 cells.

CHO-K1/CTLA4 Stable Cell Line

CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses. CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells. The CTLA-4 protein is encoded by the Ctla4 gene in mice and the CTLA4 gene in humans.

產品編號	M00530
規格	2 vials 大單詢價
數量
價格	詢價


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Description

CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses. CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.<br/>
The CTLA-4 protein is encoded by the Ctla4 gene in mice and the CTLA4 gene in humans.

Synonyms

ALPS5; CD; CD152; CELIAC3; GRD4; GSE; IDDM12

產品簡介

Stability	15 passages
Storage	Liquid nitrogen immediately upon receiving

培養條件

Culture Medium	F-12K (Kaighn’s), 10% FBS, 8 μg/ml Puromycin (Cat. #A11138-03, Gibco)
Freeze Medium-DATA	95% complete growth medium, 5% (V/V) DMSO (Cat. #D2650, Sigma)