資源 » 參考數據庫 » 客戶發表文獻

至今，GenScript的服務及產品已被Cell, Nature, Science, PNAS等1300多家生物醫藥類雜志引用近萬次，處于行業領先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學等約400家全球著名機構使用GenScript的基因合成、多肽服務、抗體服務和蛋白服務等成功地發表科研成果，再次證明GenScript 有能力幫助業內科學家Make research easy.

Efficient CRISPR-Cas9 mediated multiplex genome editing in yeasts.

Biotechnol Biofuels. 2018;

WangLaiyou，DengAihua，ZhangYun，LiuShuwen，LiangYong，BaiHua，CuiDi，QiuQidi，ShangXiuling，YangZhao，HeXiuping，WenTi

Products/Services Used	Details	Operation
Codon Optimization	4CL gene encoding 4-coumaryl-CoA ligase from Arabidopsis thaliana, STS gene encoding stilbene synthase from Vitis vinifera, and human serum albumin gene HSA were all synthesized by GenScript (Nanjing, China) in codon-optimized versions for expression in O. polymorpha.	Get A Quote

摘要

The thermotolerant methylotrophic yeast has been regarded as an important organism for basic research and biotechnological applications. It is generally recognized as an efficient and safe cell factory in fermentative productions of chemicals， biofuels and other bio-products. However， it is difficult to genetically engineer for the deficiency of an efficient and versatile genome editing technology.

關鍵詞

CRISPR–Cas9-assisted multiplex genome editing，Markerless multi-copy integration，Markerless multi-locus integration，Ogataea polymorpha，Saccharomyces cerevi

Article Link >