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Production of alkanes from CO by engineered bacteria.

Biotechnol Biofuels. 2018;

LehtinenTapio，VirtanenHenri，SantalaSuvi，SantalaV

Products/Services Used	Details	Operation
Codon Optimization	Aar (S. elongatus aar, WP_011242364.1), seado (S. elongatus ado, WP_011378104.1), pmado (P. marinus ado, WP_011130600.1) and cer1 (Arabidopsis thaliana, NP_001184890.1) were codon-optimized and purchased from Genscript (USA) with appropriate restriction sites and ribosomal binding sites (Biobrick part BBa_0034).	Get A Quote

摘要

Microbial biosynthesis of alkanes is considered a promising method for the sustainable production of drop-in fuels and chemicals. Carbon dioxide would be an ideal carbon source for these production systems， but efficient production of long carbon chains from CO is difficult to achieve in a single organism. A potential solution is to employ acetogenic bacteria for the reduction of CO to acetate， and engineer a second organism to convert the acetate into long-chain hydrocarbons.