| ￥1800 | |
| Z03807 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity |
> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
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| Endotoxin Level | Less than 1 EU per μg by the LAL method. | ||||
| Biological Activity | Immobilized TROP2, His, Human (Cat.No.: Z03807) at 0.5 μg/ml can bind Anti-TROP-2 Antibody. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 28.9 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 40-60 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the lyophilized product remains stable up to 6 months at -20 °C or below as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Immobilized TROP2, His, Human at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-TROP-2 Antibody, hFc Tag with the EC50 of 2.2/2.2/2.3 ng/ml determined by ELISA. ?
Immobilized TROP2, His, Human, His Tag at 0.5 μg/ml(100 μl/well) on the plate. Dose response curve for Anti-TROP-2 Antibody, hFc Tag with the EC50 of 3.5 ng/ml determined by ELISA. ?
The purity of TROP2, His, Human is greater than 95% as determined by SEC-HPLC. ?
TROP2, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. ?
| Target Background | The protein Trop-2, encoded by the TACSTD2 gene, is involved in tumor progression. It is overexpressed in various solid cancers including colorectal, renal, lung, and breast cancers, as well as in rare and aggressive malignancies such as salivary duct, anaplastic thyroid, uterine/ovarian, and neuroendocrine prostate cancers. |
| Synonyms | EGP1; EGP-1; TROP2; GA733-1; gp50; T16; TACSTD2; TROP-2; M1S1; TACD2 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
