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| L00402 | |
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Lipopolysaccharide
(LPS) is a bacterial endotoxin, and a major constituent of the cell walls of
gram-negative bacteria. During gram-negative bacteremia or endotoxemia, LPS is
the principal pathophysiological mediator by which bacteria can cause
hypotension, organ failure, disseminated intravascular coagulation, and fatal
shock in mammalian hosts. The removal of these endotoxins is highly necessary
for downstream processes. The ToxinEraser? Endotoxin Removal Resin utilizes immobilized polymixin B to bind and remove pyrogens from solution. The polymixins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymixin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide. |
| Product Information |
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| Key Features |
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| Storage & Stability | 2°C to 8°C (Do not freeze.) |
