資源 » 參考數(shù)據(jù)庫(kù) » 客戶發(fā)表文獻(xiàn)

至今，GenScript的服務(wù)及產(chǎn)品已被Cell, Nature, Science, PNAS等1300多家生物醫(yī)藥類雜志引用近萬(wàn)次，處于行業(yè)領(lǐng)先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學(xué)等約400家全球著名機(jī)構(gòu)使用GenScript的基因合成、多肽服務(wù)、抗體服務(wù)和蛋白服務(wù)等成功地發(fā)表科研成果，再次證明GenScript 有能力幫助業(yè)內(nèi)科學(xué)家Make research easy.

A cytoskeletal protein complex is essential for division of intracellular amastigotes of

J Biol Chem. 2020;

Felice D Kelly, Khoa D Tran, Jess Hatfield, Kat Schmidt, Marco A Sanchez, Scott M Landfear

Products/Services Used	Details	Operation
Polyclonal Antibody Services	… 5C), showing that even with both antibodies present, generation of a PLA signal requires close proximity of the two target proteins?… Generation of Rabbit anti-KH antibody A custom polyclonal anti-KH antibody was generated by GenScript, using their 49-day antibody?…	Get A Quote

摘要

Previous studies in have identified the cytoskeletal protein KHARON as being important for both flagellar trafficking of the glucose transporter GT1 and for successful cytokinesis and survival of infectious amastigote forms inside mammalian macrophages. KHARON is located in three distinct regions of the cytoskeleton: the base of the flagellum, the subpellicular microtubules, and the mitotic spindle. To deconvolve the different functions for KHARON, we have identified two partner proteins, KHAP1 and KHAP2, which associate with KHARON. KHAP1 is located only in the subpellicular microtubules, whereas KHAP2 is located at the subpellicular microtubules and the base of the flagellum. Both and null mutants are unab... More