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The interactome of porcine epidemic diarrhea virus nucleocapsid protein

research square. 2019-08;

Min Tan,Guofei Ding,Xinna Cai,Shengliang Cao,Fangyuan Cong,Jiaqi Liu,Yuzhong Zhao,Sidang Liu,Guangliang Liu,Yihong Xiao

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Catalog Antibody	… 7 ab185947) (2 μg/ antibody) was added into the supernatant and incubated for 2 h on a rotator at 4 ?C. Then the protein G resin (GenScript) were mixed overnight at 4 ?C on a rotator. The … 1. Have P, Moving V, Svansson V, Uttenthal A, Bloch B. Coronavirus infection in mink …	Get A Quote

摘要

Many viral proteins specifically interact with cellular proteins to facilitate virus replication. Understanding these interactions can decipher the viral infection mechanism and provide potential targets for antiviral therapy. Porcine epidemic diarrhea virus (PEDV), the agent of PED, causes numerous economic losses for the swine industry each year. Till now, no effective vaccine or drugs are available to contain this disease. As a result, it is critical urgent to elucidate the PEDV interactome. The nucleocapsid (N) of PEDV plays an important role in viral replication.