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Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects

Authors: Mohanraj Gopalswamy, Tobias Kroeger, David Bickel, Benedikt Frieg, Shahina Akter, Stephan Schott-Verdugo, Aldino Viegas, Thomas Pauly, Manuela Mayer, Julia Przibilla, Jens Reiners, Luitgard Nagel-Steger, Sander H J Smits, Georg Groth, Manuel Etzkorn, Holger Gohlke

Journal: Sci Rep

PubMed ID: 35986043

Doi: 10.1038/s41598-022-17913-6

Products & Services: Proteins, Expression, Isolation and Analysis

Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of PETase and Variants with Improved Stability and Activity

Authors: Yvonne Joho, Vanessa Vongsouthi, Matthew A Spence, Jennifer Ton, Chloe Gomez, Li Lynn Tan, Joe A Kaczmarski, Alessandro T Caputo, Santana Royan, Colin J Jackson, Albert Ardevol

Journal: Biochemistry

PubMed ID: 35951410

Doi: 10.1021/acs.biochem.2c00323

Products & Services: Proteins, Expression, Isolation and Analysis

Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles

Authors: Ashwanth C Francis, Anna Cereseto, Parmit K Singh, Jiong Shi, Eric Poeschla, Alan N Engelman, Christopher Aiken, Gregory B Melikyan

Journal: PLoS Pathog

PubMed ID: 35951676

Doi: 10.1371/journal.ppat.1010754

Products & Services: Proteins, Expression, Isolation and Analysis

Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene

Authors: Megan R Edwards, Olivia A Vogel, Hiroyuki Mori, Robert A Davey, Christopher F Basler