Betacellulin, Human

Betacellulin (BTC) is a member of the EGF family of growth factors that also includes EGF, TGF-α, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin, Heregulin and Neuregulins. Mature human BTC protein exhibits 80% amino acidsimilarity with mouse BTC protein. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum. It is synthesized primarily as a transmembrane precursor, which is then processed to a mature molecule by proteolytic events. BTC signals through the EGF receptor.

價(jià)格	￥400
產(chǎn)品編號(hào)	Z03244
規(guī)格	10 μg 50 μg 1 mg 大單詢價(jià)
數(shù)量

產(chǎn)品簡(jiǎn)介圖例技術(shù)背景

產(chǎn)品簡(jiǎn)介

Species

Human

Protein Construction

Expressed with an N-terminal Met.

Betacellulin (Asp32-Tyr111)
Accession # P35070

Purity

> 95% as analyzed by SDS-PAGE

Endotoxin Level

< 0.2 EU/μg of protein by gel clotting method

Biological Activity

The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is < 0.01 ng/ml, corresponding to a specific activity of >1.0 x 10⁸ units/mg.

Expression System

E. coli

Apparent Molecular Weight

~15 kDa, on SDS-PAGE under reducing conditions.

Formulation

Lyophilized after extensive dialysis against PBS.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

圖例

技術(shù)背景

Target Background

Synonyms

BTC

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

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Betacellulin, Human

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