PDGF-DD, Human

PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rβ homodimers and PDGF Rα/β heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.

價(jià)格	￥600
產(chǎn)品編號(hào)	Z03195
規(guī)格	10 μg 50 μg 大單詢價(jià)
數(shù)量

產(chǎn)品簡(jiǎn)介圖例技術(shù)背景

產(chǎn)品簡(jiǎn)介

Species

Human

Protein Construction

PDGF-DD (Ser250-Arg370)
Accession # Q9GZP0

Purity

> 95% as analyzed by SDS-PAGE

Endotoxin Level

< 0.2 EU/μg of protein by gel clotting method

Biological Activity

ED₅₀ < 5.0 μg/ml, measured in a cell proliferation assay using 3T3 cells.

Expression System

CHO

Apparent Molecular Weight

19~21 kDa, on SDS-PAGE under reducing conditions.

Formulation

Lyophilized after extensive dialysis against PBS.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

圖例

技術(shù)背景

Target Background

Synonyms

PDGFDD; IEGF; SCDGF-B; SCDGFB; MSTP036; platelet derived growth factor D

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

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PDGF-DD, Human

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