Amphiregulin, Human

Amphiregulin is a member of the EGF family of cytokines, which comprises at least ten proteins including EGF, TGF-α, HB-EGF, Epiregulin, Tomoregulin, Neuregulins and the various heregulins. Through the EGF/TGF-α receptor, it stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein.

價格	￥300
產(chǎn)品編號	Z03103
規(guī)格	10 μg 50 μg 大單詢價
數(shù)量

產(chǎn)品簡介圖例技術(shù)背景

產(chǎn)品簡介

Species

Human

Protein Construction

Amphiregulin (Ser101-Lys198)
Accession # Q5U026

Purity

> 95% as analyzed by SDS-PAGE

Endotoxin Level

< 0.2 EU/μg of protein by gel clotting method

Biological Activity

ED₅₀ < 0.2 ng/ml, measured in a cell proliferation assay using 3T3 cells.

Expression System

HEK 293

Apparent Molecular Weight

15~20 kDa, on SDS-PAGE under reducing conditions.

Formulation

Lyophilized after extensive dialysis against PBS.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

圖例

技術(shù)背景

Target Background

Synonyms

AR; AREG; Colorectum cell-derived growth factor (CRDGF)

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

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Amphiregulin, Human

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