| ￥1050 | |
| RC00007 | |
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| Description | PE6C focuses on enhancing the performance of prime editing in transgenic rice plants. This specific variant of the prime editing technology is tailored to address the challenges of genetic improvement in crops, contributing to enhanced editing precision and efficiency in agricultural applications. The effectiveness of PE6c stems from its design improvements that enable it to facilitate targeted insertions and modifications in plant genomes. |
| single guide RNA (sgRNA) dependent single-stranded DNA cleavage |
| References | David R Liu, et al. “Phage-assisted evolution and protein engineering yield compact, efficient prime editors”. Cell. 2023 Aug 31;186(18):3983-4002.e26. |
| Purity | ≥90% by SDS-PAGE, 92% by SEC-HPLC |
| Residual DNase | Non-specific DNase activity |
| Endotoxin Level | Control <10EU/mg |
| Expression System | Recombinant Cas9-based fusion with three NLS expressed by E.coli |
| Species | S. pyogenes |
| Tag | C-His tag |
| Molecular Weight | 226.54KDa |
| Storage & Stability | PE6C is supplied with storage buffer (50 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.5, at 25°C) and recommended to be stored at -80°C. |
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