国产精品久久久久久永久牛牛,55国产福利在线视频,成人午夜精品视频在线观看

至今,GenScript的服務(wù)及產(chǎn)品已被Cell, Nature, Science, PNAS等1300多家生物醫(yī)藥類雜志引用近萬次,處于行業(yè)領(lǐng)先水平。NIH、哈佛、耶魯、斯坦福、普林斯頓、杜克大學(xué)等約400家全球著名機(jī)構(gòu)使用GenScript的基因合成、多肽服務(wù)、抗體服務(wù)和蛋白服務(wù)等成功地發(fā)表科研成果,再次證明GenScript 有能力幫助業(yè)內(nèi)科學(xué)家Make research easy.

Dimerization and antidepressant recognition at noradrenaline transporter

Nature. 2024-05; 
Heng Zhang # 1, Yu-Ling Yin # 2, Antao Dai # 3 4, Tianwei Zhang 2 5, Chao Zhang 4 6, Canrong Wu 1, Wen Hu 1 7, Xinheng He 1 8, Benxun Pan 2, Sanshan Jin 2, Qingning Yuan 1 7, Ming-Wei Wang 9 10 11, Dehua Yang 12 13 14, H Eric Xu 15 16 17, Yi Jiang 18 19
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis The competitive binding of nisoxetine to NET protein was assessed using anti-DYKDDDDK G1 Affinity Resin (GenScript). Get A Quote

摘要

The noradrenaline transporter has a pivotal role in regulating neurotransmitter balance and is crucial for normal physiology and neurobiology1. Dysfunction of noradrenaline transporter has been implicated in numerous neuropsychiatric diseases, including depression and attention deficit hyperactivity disorder2. Here we report cryo-electron microscopy structures of noradrenaline transporter in apo and substrate-bound forms, and as complexes with six antidepressants. The structures reveal a noradrenaline transporter dimer interface that is mediated predominantly by cholesterol and lipid molecules. The substrate noradrenaline binds deep in the central binding pocket, and its amine group interacts with a conserved a... More

關(guān)鍵詞

              主站蜘蛛池模板: 镇远县| 明水县| 两当县| 庄河市| 来宾市| 济宁市| 屏边| 吉安县| 保靖县| 连江县| 沂南县| 金华市| 普陀区| 乌拉特后旗| 大余县| 五大连池市| 石景山区| 黔江区| 廊坊市| 鄂尔多斯市| 陕西省| 新巴尔虎左旗| 新晃| 宜昌市| 黑水县| 乌苏市| 黄浦区| 寿宁县| 许昌市| 龙川县| 隆昌县| 宝兴县| 丰原市| 昔阳县| 无为县| 成安县| 那曲县| 武清区| 蒙山县| 平南县| 池州市|