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目錄產品 » Human Kappa Light Chain (2F1C1), mAb, Mouse

Human Kappa Light Chain (2F1C1), mAb, Mouse

Immunoglobulins (Ig) and free light chains (FLC) is involved in humoral immune response. Ig is composed of two identical light chains and two identical heavy chains. FLC contains two types: kappa free light chain (KFLC) and lambda free light chain (LFLC). The expression of Kappa or Lambda is greatly increased in multiple myeloma or other B cell malignancies. It is useful for the identification of certain non-Hodgkin’s lymphomas, leukemias and plasmacytomas. Immunohistochemistry is commonly applied for the detection of free light chains.
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Description

Immunoglobulins (Ig) and free light chains (FLC) is involved in humoral immune response. Ig is composed of two identical light chains and two identical heavy chains. FLC contains two types: kappa free light chain (KFLC) and lambda free light chain (LFLC). The expression of Kappa or Lambda is greatly increased in multiple myeloma or other B cell malignancies. It is useful for the identification of certain non-Hodgkin’s lymphomas, leukemias and plasmacytomas. Immunohistochemistry is commonly applied for the detection of free light chains.
Synonyms

Human Kappa Light Chain (2F1C1), mAb, Mouse

Note

GenScript can customize this product per customer's request including product size, buffer components,etc.

Specificity Specific to Human Kappa light chain, does not react with human Lambda light chain
Subclass IgG1
Host Species Mouse
Conjugation Unconjugated
Antigen Species Human

Production Cultured in vitro under conditions free from animal-derived components
Purification Protein A/G affinity column
Formulation 1) PBS, pH 7.4, containing 0.03% Proclin 300
2) 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300 *
*: For new batch since 09/01/2018, please refer to COA.
Concentration ≥2mg/ml
Clone ID 2F1C1
Storage For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

ELISA/IHC/Flow cytometry assay

Target Background Immunoglobulins (Ig) and free light chains (FLC) is involved in humoral immune response. Ig is composed of two identical light chains and two identical heavy chains. FLC contains two types: kappa free light chain (KFLC) and lambda free light chain (LFLC). The expression of Kappa or Lambda is greatly increased in multiple myeloma or other B cell malignancies. It is useful for the identification of certain non-Hodgkin’s lymphomas, leukemias and plasmacytomas. Immunohistochemistry is commonly applied for the detection of free light chains.


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